Epilepsia 2019, 60 (7): 1293-1305

Network Concept from an Imaging Perspective

Wykes RC*, Khoo HM, Caciagli L, Blumenfeld H, Golshani P, Kapur J, Mehta A, Stern J, Bernasconi A, Dedeurwaerdere S & Bernasconi N

Neuroimaging techniques applied to a variety of organisms—from zebrafish, to rodents to humans—can offer valuable insights into neuronal network properties and their dysfunction in epilepsy. A wide range of imaging methods used to monitor neuronal circuits and networks during evoked seizures in animal models and advances in functional magnetic resonance imaging (fMRI) applied to patients with epilepsy were discussed during the XIV Workshop on Neurobiology of Epilepsy (XIV WONOEP) organized in 2017 by the Neurobiology Commission of the International League Against Epilepsy (ILAE). We review the growing number of technological approaches developed, as well as the current state of knowledge gained from studies applying these advanced imaging approaches to epilepsy research.