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The Nanomedicine Lab 2.0 Mission is to generate and disseminate fundamental knowledge in the field of nanomedicine by convergence of nanotechnology, bioengineering, pharmacology, neuroscience, cell biology, omics and their translation to advanced, clinically relevant and safe therapeutics and diagnostics

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RESEARCH TEAMS

The NanoOmics Team aims to harness the interactions of nanomaterials with blood components
The NanoInflammation Team studies how nanomaterials may cause inflammation or be used to modulate inflammation and control disease
The NanoCell Biology Team unveils interactions of nanomaterials with living cells and their structural compartments
The NanoNeuro Team studies the use of graphene-based neural interface technologies in the neurophysiology of brain disorders
The NanoTherapeutics Team exploits the unique properties of nanoparticles to develop clinically translatable advanced medicines
The Nanomedicine@ICN2 Team designs, fabricates and characterizes advanced nanomaterials at biological grade for medical use

RECENT PUBLICATIONSVIEW ALL

Nanoscale, 2022, in press

Graphene oxide modulates dendritic cell ability to promote T cell activation and cytokine production

Helen Parker, Alfredo Gravagnuolo, Sandra Vranic, Livia Crica, Leon Newman, Oliver Carnell, Cyrill Bussy, Rebecca Dookie, Eric Prestat, Sarah Haigh, Neus Lozano, Kostas Kostarelos*, Andrew MacDonald*

FULL ABSTRACT

Advanced Healthcare Materials, 2022, 2201968

Graphene oxide nanoscale platform enhances the anti-cancer properties of bortezomib in glioblastoma models

Paul Sharp^, Maria Stylianou^, Luis Arellano, Juliana Neves, Alfredo Gravagnuolo, Abbie Dodd, Katharine Barr, Neus Lozano, Thomas Kisby*, Kostas Kostarelos*

FULL ABSTRACT

Methods in Molecular Biology, 2022, 2565, 13, 187-202

Membrane Capacitance Measurements of Stimulus-Evoked Exocytosis in Adrenal Chromaffin Cells

Elizabeth P. Seward, Robert C. Wykes

FULL ABSTRACT

ACS Appl. Nano Mater. 2022, 5 (9): 12626–12636

Effects of lateral size, thickness, and stabilizer concentration on the cytotoxicity of defect-free graphene nanosheets: implications for biological applications

Chen-Xia Hu, Oliver Read, Yuyoung Shin, Yingxian Chen, Jingjing Wang, Matthew Boyes, Niting Zeng, Adyasha Panigrahi, Kostas Kostarelos, Igor Larrosa, Sandra Vranic*, Cinzia Casiraghi*

FULL ABSTRACT

Nature Nanotechnology, 2022, in press

Graphene oxide elicits microbiome-dependent type 2 immune responses via the aryl hydrocarbon receptor

Guotao Peng, Hanna Sinkko, Harri Alenius, Neus Lozano, Kostas Kostarelos, Lars Bräutigam, Bengt Fadeel*

FULL ABSTRACT

DMM Disease Models and Mechanisms, 2022, 15 (10): dmm049703

Targeting firing rate neuronal homeostasis can prevent seizures

Fred Mulroe, Wei-Hsiang Lin, Connie Mackenzie-Gray Scott, Najat Aourz, Yuen Ngan Fan, Graham Coutts, R Ryley Parrish, Ilse Smolders, Andrew Trevelyan, Rob Wykes, Stuart Allan, Sally Freeman, Richard Baines

FULL ABSTRACT

Particle and Fibre Toxicology, 2022, 19 (1), 1-21

Lung recovery from DNA damage induced by graphene oxide is dependent on size, dose and inflammation profile

Luis Augusto Visani de Luna, Thomas Loret, Alexander Fordham, Atta Arshad, Matthew Drummond, Abbie Dodd, Neus Lozano, Kostas Kostarelos and Cyrill Bussy

FULL ABSTRACT

Frontiers in Computational Neuroscience, 2022, 16, 900063

Impact of DC-coupled electrophysiological recordings for translational neuroscience: Case study of tracking neural dynamics in rodent models of seizures

Amirhossein Jafarian and Rob C. Wykes

FULL ABSTRACT

Clinical and Translational Medicine, 2022, 12(7), e968

The advantages of mapping slow brain potentials using DC-coupled graphene micro-transistors: Clinical and translational applications

Robert C. Wykes, Eduard Masvidal-Codina, Anton Guimerà-Brunet and Jose. A Garrido

FULL ABSTRACT

Nature Reviews Clinical Oncology, 2022, 19(8), 551-561

Nano-omics: Nanotechnology-based multidimensional harvesting of the blood-circulating cancerome

Lois Gardner, Kostas Kostarelos, Parag Mallick, Caroline Dive and Marilena Hadjidemetriou

FULL ABSTRACT

RECENT NEWSVIEW ALL

29/10/2022

Aswin, Thomas and Cyrill participated in Manchester’s ScienceX festival, organised by the University of Manchester, sharing knowledge and tips for reducing the impact of microplastics to Human health and the Environment, as part of the communication activities of the EU project PLASTICHEAL funded by the H2020 framework programme of the European Commission.

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28/10/2022

Rob attends a webinar for Epilepsy Sparks

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21/10/2022

Rahaf presents at the Graphene Flagship WP4 meeting in Greece

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Neus Lozano, team leader @ICN2, assists to the MINIGRAPH kick-off meeting

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19/10/2022

Nanomedicine Lab @ICN2 receives the visit of Dr. Dhifaf Jasim

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18/10/2022

Noelia Hernández assists to Prof. Dr. Farideh Jalilehvand seminar at UAB

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14/10/2022

Kostas is interviewed by Global Banking & Finance Review about smart materials and artificial intelligence are taking us closer to understanding the human brain

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10/10/2022

Rob presents at the Co-Operative Studies on Brain Injury Depolarisations (COSBID) meeting in Salt Lake City, USA

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06/10/2022

Hanan presented her project in the CRUK Radnet biannual meeting

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