Peptide nanofibres as molecular transporters: From self-assembly to in vivo degradation

Faraday Discussions, 2013, 166, 181-194

Peptide nanofibres as molecular transporters: From self-assembly to in vivo degradation

Mariarosa Mazza, Avnish Patel, Ramon Pons, Cyrill Bussy and Kostas Kostarelos

In this report, we describe the self-assembly of PNFs by using palmitoyl-peptide molecules containing two different cationic amino acid sequences and offer a description of the nanofiber physicochemical characteristics. Overall, the self-assembled PNFs were seen to internalise within neurons and be removed or degrade in the brain. Further work is needed to determine the utility of such PNFs as molecular transporters within neuronal tissue.

LAB PUBLICATIONSVIEW ALL

Nature Reviews Clinical Oncology, 2025, in press

Glioblastoma resection margin as a therapeutic target and the opportunity for locoregional nanotechnologies

Thomas Kisby, Gerben R. Borst, David J. Coope, Kostas Kostarelos*

FULL ABSTRACT

Small, 2025, in press

Safety assessment of graphene-based materials

Bengt Fadeel*, James Baker, Laura Ballerini, Cyrill Bussy, Fabio Candotto Carniel, Mauro Tretiach, Marco Pelin, Tina Buerki-Thurnherr, Tomi Kanerva, José Maria Navas, Ester Vázquez, Virginia Rodriguez Unamuno, Panja Lehtonen, Mar González, Hubert Rauscher, Juan Riego Sintes, Kostas Kostarelos, Alberto Bianco*, Maurizio Prato*

FULL ABSTRACT

Nature Reviews Chemistry, 2025, in press

The challenge and necessity of biological and environmental degradation for two-dimensional materials

Sandra Vranic^, Rajendra Kurapati^, Kostas Kostarelos*, Alberto Bianco*

FULL ABSTRACT

Diamond and Related Materials, 2024, 150, 111722

The impact of graphene oxide nanosheet lateral dimensions on the electrochemical performance of nanoporous graphene-based electrodes

María del Pilar Bernicola, Miquel Madrid-Gimeno, Nerea Murillo-Cremaes, Tommaso Battisti, Neus Lozano, Kostas Kostarelos, Jose A. Garrido*, Elena del Corro*

FULL ABSTRACT

Nano Today, 2024, 56:102254

Functioning human lung organoids model pulmonary tissue response from carbon nanomaterial exposures

Rahaf Issa, Neus Lozano, Kostas Kostarelos, Sandra Vranic*

FULL ABSTRACT

Nature Reviews Materials, 2024, 9, 219–222

In vivo biomolecule corona and the transformation of a foe into an ally for nanomedicine

Marilena Hadjidemetriou, Morteza Mahmoudi*, Kostas Kostarelos*

FULL ABSTRACT

Nature Nanotechnology, 2024, 19, 705–714

First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses

Jack Andrews^, Shruti Joshi^, Evangelos Tzolos, Maaz Syed, Hayley Cuthbert, Livia Crica, Neus Lozano, Emmanuel Okwelogu, Jennifer Raftis, Lorraine Bruce, Craig Poland, Rodger Duffin, Paul Fokkens, John Boere, Daan Leseman, Ian Megson, Phil D. Whitfield, Kerstin Ziegler, Seshu Tammireddy, Marilena Hadjidemetriou, Cyrill Bussy, Flemming Cassee, David Newby, Kostas Kostarelos*, Mark Miller*

FULL ABSTRACT

ACS Nano, 2024, 18, 6038-6094

Environmental and health impacts of graphene and other two-dimensional materials: a Graphene Flagship perspective

Hazel Lin, Tina Buerki-Thurnherr, Jasreen Kaur, Peter Wick, Marco Pelin, Aurelia Tubaro, Fabio Candotto Carniel, Mauro Tretiach, Emanuel Flahaut, Daniel Iglesias, Ester Vázquez, Giada Cellot, Laura Ballerini, Valentina Castagnola, Fabio Benfenati, Andrea Armirotti, Antoine Sallustrau, Mathilde Keck, Frédéric Taran, Cyrill Bussy, Sandra Vranic, Kostas Kostarelos, Mona Connolly, José Maria Navas, Florence Mouchet, Laury Gauthier, James Baker, Blanca Suarez-Merino, Tomi Kanerva, Maurizio Prato, Bengt Fadeel*, Alberto Bianco*

FULL ABSTRACT

Nature Reviews Electrical Engineering, 2024, 1, 75-76

Clinical translation of graphene-based medical technology

Kostas Kostarelos, Carolina Aguilar, and Jose Garrido*

FULL ABSTRACT

Nature Nanotechnology 2024, 19, 514–523

Nanoporous graphene-based thin-film microelectrodes for in vivo high-resolution neural recording and stimulation

Damià Viana^, Steven T. Walston^, Eduard Masvidal-Codina^, Xavier Illa, Bruno Rodríguez-Meana, Jaume del Valle, Andrew Hayward, Abbie Dodd, Thomas Loret, Elisabet Prats-Alfonso, Natàlia de la Oliva, Marie Palma, Elena del Corro, María del Pilar Bernicola, Elisa Rodríguez-Lucas, Thomas A. Gener, Jose Manuel de la Cruz, Miguel Torres-Miranda, Fikret Taygun Duvan, Nicola Ria, Justin Sperling, Sara Martí-Sánchez, Maria Chiara Spadaro, Clément Hébert, Sinead Savage, Jordi Arbiol, Anton Guimerà-Brunet, M. Victoria Puig, Blaise Yvert, Xavier Navarro, Kostas Kostarelos*, Jose A. Garrido*

FULL ABSTRACT

Peptide nanofibres as molecular transporters: From self-assembly to in vivo degradation

SHARE THIS

LAB PUBLICATIONSVIEW ALL

Glioblastoma resection margin as a therapeutic target and the opportunity for locoregional nanotechnologies

Safety assessment of graphene-based materials

The challenge and necessity of biological and environmental degradation for two-dimensional materials

The impact of graphene oxide nanosheet lateral dimensions on the electrochemical performance of nanoporous graphene-based electrodes

Functioning human lung organoids model pulmonary tissue response from carbon nanomaterial exposures

In vivo biomolecule corona and the transformation of a foe into an ally for nanomedicine

First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses

Environmental and health impacts of graphene and other two-dimensional materials: a Graphene Flagship perspective

Clinical translation of graphene-based medical technology

Nanoporous graphene-based thin-film microelectrodes for in vivo high-resolution neural recording and stimulation

PART OF