Carbon nanotubes in macrophages: Imaging and chemical analysis by X-ray fluorescence microscopy

Nano Letters, 2008, 8(9), 2659-2663

Carbon nanotubes in macrophages: Imaging and chemical analysis by X-ray fluorescence microscopy

Cyrill Bussy, Julien Cambedouzou, Sophie Lanone, Emilie Leccia, Vasile Heresanu, Mathieu Pinault, Martine Mayne-l’Hermite, Nathalie Brun, Claudie Mory, Marine Cotte, Jean Doucet, Jorge Boczkowski and Pascale Launois

X-ray fluorescence microscopy (μXRF) is applied for the first time to study macrophages exposed to unpurified and purified single-walled (SW) and multiwalled (MW) carbon nanotubes (CNT). Investigating chemical elemental distributions allows one to (i) image nanotube localization within a cell and (ii) detect chemical modification of the cell after CNT internalization. An excess of calcium is detected for cells exposed to unpurified SWCNT and MWCNT and related toxicological assays are discussed.

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Carbon nanotubes in macrophages: Imaging and chemical analysis by X-ray fluorescence microscopy

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RECENT PUBLICATIONSVIEW ALL

Functioning human lung organoids model pulmonary tissue response from carbon nanomaterial exposures

In vivo biomolecule corona and the transformation of a foe into an ally for nanomedicine

First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses

Graphene oxide activates canonical TGFβ signalling in a human chondrocyte cell line via increased plasma membrane tension

Environmental and health impacts of graphene and other two-dimensional materials: a Graphene Flagship perspective

Clinical translation of graphene-based medical technology

Nanoporous graphene-based thin-film microelectrodes for in vivo high-resolution neural recording and stimulation

Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets

Pulmonary toxicity of boron nitride nanomaterials is aspect ratio dependent

Delivery of graphene oxide nanosheets modulates glutamate release and normalizes amygdala synaptic plasticity to improve anxiety-related behavior

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