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The Nanomedicine Lab has a mission to generate and disseminate fundamental knowledge in the field of nanomedicine at the convergence of nanotechnology, bioengineering, pharmacology and neurotechnology. 

Clinical translation of advanced materials as integral components of next generation therapeutics, diagnostics and medical devices by safe and socially responsible pathways is our ultimate goal.

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LAB PUBLICATIONSVIEW ALL

bioRxiv, 2025, in press

Graphene micro-transistor arrays reveal perfusion-dependent electrophysiological and haemodynamic signatures of cortical spreading depolarizations in ischaemic stroke

S. Flaherty, A. Eladly, K. Hills, J. Merlini, E. Masvidal-Codina, E. Fernandez, X. Illa, E. Prats-Alfonso, E. Del Corro, J.A. Garrido, J. Meents, K. Kostarelos, S Allan, A. Guimerà-Brunet*, R.C. Wykes*

FULL ABSTRACT

Nature Reviews Clinical Oncology, 2025, 22

Targeting the glioblastoma resection margin with locoregional nanotechnologies

Thomas Kisby, Gerben R. Borst, David J. Coope, Kostas Kostarelos*

FULL ABSTRACT

Journal of Nanobiotechnology 23, 393 (2025)

Interplay between material properties and cellular effects drives distinct pattern of interaction of graphene oxide with cancer and non-cancer cells

Yingxian Chen, Vinicio Rosano, Neus Lozano, YuYoung Shin, Aleksandr Mironov, David Spiller, Cinzia Casiraghi, Kostas Kostarelos*, Sandra Vranic*

FULL ABSTRACT

bioRxiv, 2025, in press

An artefact-resilient wide bandwidth bidirectional graphene neural interface

Michał Prokop, Martín Esparza-Iaizzo, Eduard Masvidal-Codina, Xavi Illa, Neela K. Codadu, Daman Rathore, Nicola Ria, Kostas Kostarelos, Elena del Corro, Ramon Garcia-Cortadella, Rob C. Wykes, Anton Guimerà-Brunet*, Jose A. Garrido*

FULL ABSTRACT

bioRxiv, 2025, in press

Targeting therapeutic nanoparticles to the glioblastoma resection margin by harnessing post-operative spatiotemporal blood-brain barrier disruption

Lorena F. Fernandes, Chariya Peeyatu, Ben R. Dickie, Yu Siong Ho, Lydia A. Thompson, Noelia Hernandez, Neus Lozano, Kostas Kostarelos*, Thomas Kisby*

FULL ABSTRACT

Nature Communications, 2025, 16, 3412

Plasma-to-tumour tissue integrated proteomics using nano-omics for biomarker discovery in glioblastoma

Xinming Liu, Hanan Abmanhal-Masarweh, Olivia Iwanowytsch, Emmanuel Okwelogu, Kiana Arashvand, Konstantina Karabatsou, Pietro I D'Urso, Federico Roncaroli, Kostas Kostarelos, Thomas Kisby*, Marilena Hadjidemetriou*

FULL ABSTRACT

Nature Communications, 2025, 16, 2891

Flexible graphene-based neurotechnology for high-precision deep brain mapping and neuromodulation in Parkinsonian rats

Nicola Ria, Ahmed Eladly, Eduard Masvidal, Xavi Illa, Anton Guimerà, Kate Hills, Ramon Garcia, Fikret Taygun Duvan, Samuel Flaherty, Michal Prokop, Rob. C Wykes*, Kostas Kostarelos*, Jose A. Garrido*

FULL ABSTRACT

Cell Reports Physical Science, 2025, 6, 1, 1102342

Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets

Maria Stylianou, Thomas Kisby*, Despoina Despotopoulou, Helen Parker, Alexandra Thawley, Kiana Arashvand, Neus Lozano, Andrew S. MacDonald, Kostas Kostarelos*

FULL ABSTRACT

ACS Nano 2025, 19, 11, 10630–10717

Interfacing with the brain: How nanotechnology can contribute

Abdullah A. A. Ahmed, Nuria Alegret, Bethany Almeida, Ramon Alvarez-Puebla, Anne M. Andrews, Laura Ballerini, Juan J. Barrios-Capuchino, Charline Becker, Robert H. Blick, Shahin Bonakdar, Indranath Chakraborty, Xiaodong Chen, Jinwoo Cheon, Gerwin Chilla, Andre Luiz Coelho Conceicao, James Delehanty, Martin Dulle, Alexander L. Efros, Matthias Epple, Mark Fedyk, Neus Feliu, Miao Feng, Rafael Fernandez-Chacon, Irene Fernandez-Cuesta, Niels Fertig, Stephan Forster, Jose A. Garrido, Michael George, Andreas H. Guse, Norbert Hampp, Jann Harberts, Jili Han, Hauke R. Heekeren, Ulrich G. Hofmann, Malte Holzapfel, Hessam Hosseinkazemi, Yalan Huang, Patrick Huber, Taeghwan Hyeon, Sven Ingebrandt, Marcello Ienca, Armin Iske, Yanan Kang, Gregor Kasieczka, Dae-Hyeong Kim, Kostas Kostarelos, Jae-Hyun Lee, Kai-Wei Lin, Sijin Liu, Xin Liu, Yang Liu, Christian Lohr, Volker Mailander, Laura Maffongelli, Saad Megahed, Alf Mews, Marina Mutas, Leroy Nack, Nako Nakatsuka, Thomas G. Oertner, Andreas Offenhauser, Martin Oheim, Ben Otange, Ferdinand Otto, Enrico Patrono, Bo Peng, Alessandra Picchiotti, Filippo Pierini, Monika Potter-Nerger, Maria Pozzi, Arnd Pralle, Maurizio Prato, Bing Qi, Pedro Ramos-Cabrer, Ute Resch Genger, Norbert Ritter, Marten Rittner, Sathi Roy, Francesca Santoro, Nicolas W. Schuck, Florian Schulz, Erkin Seker, Marvin Skiba, Martin Sosniok, Holger Stephan, Ruixia Wang, Ting Wang, K. David Wegner, Paul S. Weiss, Ming Xu, Chenxi Yang, Seyed Shahrooz Zargarian, Yuan Zeng, Yaofeng Zhou, Dingcheng Zhu, Robert Zierold, Wolfgang J. Parak*

FULL ABSTRACT

Nature Reviews Chemistry, 2025, 9, 173–184

Biological and environmental degradation of two-dimensional materials

Sandra Vranic^, Rajendra Kurapati^, Kostas Kostarelos*, Alberto Bianco*

FULL ABSTRACT

LAB SEMINARS

The Nanomedicine Lab regularly invites experts from diverse academic, research and industrial institutions, either as contributions to institutional seminar series or visiting the Lab and its facilities.

14/02/2025

Nanoscale optics with plasmonic lattices

Prof. Teri W. Odom

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10/06/2024

Synthesis and application of 1D vdW heterostructures based on single-walled carbon nanotubes

Prof. Shigeo Maruyama

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13/07/2023

Boosting 2D materials with molecules: from high-performance multiresponsive electronics to pressure sensing for health monitoring

Prof. Paolo Samorì

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03/03/2023

Microfluidic manufacturing of nanoparticles: production considerations

Prof. Yvonne Perrie

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26/01/2023

Injury programmes shape glioblastoma

Prof. Simona Parrinello

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14/07/2022

Flexible electronics for neural interfaces

Prof. Jonathan Viventi

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21/04/2022

The Robotics Part of Micro and Nano Robotics

Prof. Bradley Nelson

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10/03/2022

Barcoded Nanoparticles for Precision Cancer Medicine: Effects of tumor type and patient sex on anticancer efficacy

Prof. Avi Schroeder

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27/01/2022

Micro/Nano engineering and drug delivery

Prof. Anja Boisen

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25/11/2021

Technology for bioelectronic medicine

Prof. George Malliaras

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14/10/2021

Translational research in organic neuroprosthetics

Prof. Diego Ghezzi

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13/02/2020

Directed growth and assembly of gold nanocrystals for bioapplications

Prof. Luis Liz-Marzán

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LAB NEWSVIEW ALL

10/06/2025

Nanomedicine at the EU IndTech conference in Kraków

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05/06/2025

Inspiring the next generation of scientists!

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03/06/2025

Despoina gives a talk at the Intracranial Glioma Workshop

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29/05/2025

Kostas speaks at the 20-year anniversary of the ETPN (NME25) meeting in Barcelona

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27/05/2025

José and Kostas receive the 2024 City of Barcelona Award in Science and Technology

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13/05/2025

SKIN2DTRONICS Kick-off meeting

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06/05/2025

Nanosolutions in Oncology Severo Ochoa Workshop

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24/04/2025

Seminar at the Institute of NeuroPhysiopathology in Marseille

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08/04/2025

The Lab goes on a retreat!

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