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The Nanomedicine Lab has a mission to generate and disseminate fundamental knowledge in the field of nanomedicine at the convergence of nanotechnology, bioengineering, pharmacology and neurotechnology. 

Clinical translation of advanced materials as integral components of next generation therapeutics, diagnostics and medical devices by safe and socially responsible pathways is our ultimate goal.

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LAB PUBLICATIONSVIEW ALL

Nature Reviews Chemistry, 2024, in press

The challenge and necessity of biological and environmental degradation for two-dimensional materials

Sandra Vranic^, Rajendra Kurapati^, Kostas Kostarelos*, Alberto Bianco*

FULL ABSTRACT

Nano Today, 2024, 56:102254

Functioning human lung organoids model pulmonary tissue response from carbon nanomaterial exposures

Rahaf Issa, Neus Lozano, Kostas Kostarelos, Sandra Vranic*

FULL ABSTRACT

Nature Reviews Materials, 2024, 9, 219–222

In vivo biomolecule corona and the transformation of a foe into an ally for nanomedicine

Marilena Hadjidemetriou, Morteza Mahmoudi*, Kostas Kostarelos*

FULL ABSTRACT

Nature Nanotechnology, 2024, 19, 705–714

First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses

Jack Andrews^, Shruti Joshi^, Evangelos Tzolos, Maaz Syed, Hayley Cuthbert, Livia Crica, Neus Lozano, Emmanuel Okwelogu, Jennifer Raftis, Lorraine Bruce, Craig Poland, Rodger Duffin, Paul Fokkens, John Boere, Daan Leseman, Ian Megson, Phil D. Whitfield, Kerstin Ziegler, Seshu Tammireddy, Marilena Hadjidemetriou, Cyrill Bussy, Flemming Cassee, David Newby, Kostas Kostarelos*, Mark Miller*

FULL ABSTRACT

ACS Nano, 2024, 18, 6038-6094

Environmental and health impacts of graphene and other two-dimensional materials: a Graphene Flagship perspective

Hazel Lin, Tina Buerki-Thurnherr, Jasreen Kaur, Peter Wick, Marco Pelin, Aurelia Tubaro, Fabio Candotto Carniel, Mauro Tretiach, Emanuel Flahaut, Daniel Iglesias, Ester Vázquez, Giada Cellot, Laura Ballerini, Valentina Castagnola, Fabio Benfenati, Andrea Armirotti, Antoine Sallustrau, Mathilde Keck, Frédéric Taran, Cyrill Bussy, Sandra Vranic, Kostas Kostarelos, Mona Connolly, José Maria Navas, Florence Mouchet, Laury Gauthier, James Baker, Blanca Suarez-Merino, Tomi Kanerva, Maurizio Prato, Bengt Fadeel*, Alberto Bianco*

FULL ABSTRACT

Nature Reviews Electrical Engineering, 2024, 1, 75-76

Clinical translation of graphene-based medical technology

Kostas Kostarelos, Carolina Aguilar, and Jose Garrido*

FULL ABSTRACT

Nature Nanotechnology 2024, 19, 514–523

Nanoporous graphene-based thin-film microelectrodes for in vivo high-resolution neural recording and stimulation

Damià Viana^, Steven T. Walston^, Eduard Masvidal-Codina^, Xavier Illa, Bruno Rodríguez-Meana, Jaume del Valle, Andrew Hayward, Abbie Dodd, Thomas Loret, Elisabet Prats-Alfonso, Natàlia de la Oliva, Marie Palma, Elena del Corro, María del Pilar Bernicola, Elisa Rodríguez-Lucas, Thomas A. Gener, Jose Manuel de la Cruz, Miguel Torres-Miranda, Fikret Taygun Duvan, Nicola Ria, Justin Sperling, Sara Martí-Sánchez, Maria Chiara Spadaro, Clément Hébert, Sinead Savage, Jordi Arbiol, Anton Guimerà-Brunet, M. Victoria Puig, Blaise Yvert, Xavier Navarro, Kostas Kostarelos*, Jose A. Garrido*

FULL ABSTRACT

bioRxiv, 2024, in press

Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets

Maria Stylianou, Thomas Kisby*, Despoina Despotopoulou, Helen Parker, Alexandra Thawley, Kiana Arashvand, Neus Lozano, Andrew MacDonald, Kostas Kostarelos*

FULL ABSTRACT

ACS Nano, 2023, 17 (24): 24919–24935

Pulmonary toxicity of boron nitride nanomaterials is aspect ratio dependent

Luis Visani^, Thomas Loret^, Yilin He, Morgan Legnani, Hazel Lin, Anne Marie Galibert, Alexander Fordham, Sonja Holme, Antonio Castillo, Francesco Bonaccorso, Alberto Bianco*, Emmanuel Flahaut*, Kostas Kostarelos*, Cyrill Bussy*

FULL ABSTRACT

Nanoscale, 2023, 15, 18581

Delivery of graphene oxide nanosheets modulates glutamate release and normalizes amygdala synaptic plasticity to improve anxiety-related behavior

Elisa Pati, Audrey Franceschi Biagioni, Raffaele Casani, Neus Lozano, Kostas Kostarelos, Giada Cellot*, Laura Ballerini*

FULL ABSTRACT

LAB SEMINARS

The Nanomedicine Lab regularly invites experts from diverse academic, research and industrial institutions, either as contributions to institutional seminar series or visiting the Lab and its facilities.

10/06/2024

Synthesis and application of 1D vdW heterostructures based on single-walled carbon nanotubes

Prof. Shigeo Maruyama

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13/07/2023

Boosting 2D materials with molecules: from high-performance multiresponsive electronics to pressure sensing for health monitoring

Prof. Paolo Samorì

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03/03/2023

Microfluidic manufacturing of nanoparticles: production considerations

Prof. Yvonne Perrie

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26/01/2023

Injury programmes shape glioblastoma

Prof. Simona Parrinello

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14/07/2022

Flexible electronics for neural interfaces

Prof. Jonathan Viventi

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21/04/2022

The Robotics Part of Micro and Nano Robotics

Prof. Bradley Nelson

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10/03/2022

Barcoded Nanoparticles for Precision Cancer Medicine: Effects of tumor type and patient sex on anticancer efficacy

Prof. Avi Schroeder

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27/01/2022

Micro/Nano engineering and drug delivery

Prof. Anja Boisen

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25/11/2021

Technology for bioelectronic medicine

Prof. George Malliaras

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14/10/2021

Translational research in organic neuroprosthetics

Prof. Diego Ghezzi

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13/02/2020

Directed growth and assembly of gold nanocrystals for bioapplications

Prof. Luis Liz-Marzán

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LAB NEWSVIEW ALL

10/11/2024

BBC Radio 4 live interview on graphene device in the clinic

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06/11/2024

Synergy Grant award from the European Research Council (ERC) for Skin2DTronics!

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04/11/2024

The Guardian interested in how we use graphene chips in brain cancer surgery

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31/10/2024

Bloomberg features INBRAIN Neuroelectronics Series B financing

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29/10/2024

The Lab welcomes family and friends on a wonderful Community Day!

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17/10/2024

Science considers our clinical trial the latest milestone in the graphene field!

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14/10/2024

WIRED magazine runs exclusive feature on our graphene neural probes reaching the clinic

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10/10/2024

Father of carbon nanotubes Iijima-sensei is excited with our graphene-based brain implants

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07/10/2024

World first-in-human graphene medical device clinical trial launched

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